Desire to have children

What are the possible treatments?

The selection of the treatment and the chances of pregnancy depend on the anamnesis of both partners.

Gynecological Practice

Hormone therapy in the woman
Intrauterine insemination: the sperm are prepared in the laboratory and inserted into the uterus on the day of ovulation.

Center for Reproductive Medicine

Insemination with hormone stimulation

In addition, insemination outside the body is possible using various methods at the centers for reproductive medicine

In vitro fertilisation (IVF)
The eggs are incubated together with the sperm.
Intracytoplasmic sperm injection (ICSI)
A selected sperm is injected into each ovum. This method can also be used with sperm from a testicular biopsy.
Intracytoplasmic morphologically selected sperm injection (IMSI)
This sperm is selected for injection under a high-resolution microscope according to specific structural criteria.

What is the process of artificial insemination outside the body?

This is possible as a rule with hormone stimulation, also in the spontaneous cycle.
The eggs are retrieved in the laboratory or in the hospital and fertilized on the same day using the selected method with the sperm of the partner.
Optional pre-implantation genetic diagnosis: molecular genetic polar body diagnosis of the oocytes to exclude aneuploidia (maldistribution of chromosomes) using VeriSeq PGS (Illumina verifi® technology). Trophectoderm biopsies are possible from 01.09.2017.
After 2 to 5 days, 1-3 embryos are returned into the uterus.
Excess fertilized embryos can be frozen for later treatment and / or for another child.

	What are the possible causes?	What are the possible causes?
In the woman	Age Hormonal situation Endometriosis, myoma,blocked fallopian tubes	Assessment of the menstrual cycle and hormonal analyses Ultrasound and possibly x-ray examination of the uterus, fallopian tubes and ovaries
In the man	Impairment of sperm production (hormone disorder, undescended testicles, genetic predispositions, tumors, chemotherapy / radiotherapy) Varicose veins in the scrotum	Semen analysis Depending on the result: determination of DNA fragmentation, probatory preparation, biochemical analyses of the seminal plasma, hormonal analyses If applicable, further urological / andrological investigations
In both partners	Harmful substances and stimulants in excess: nicotine, alcohol, drugs, environmental toxins Venereal diseases, infections	Investigations into current or past urogenital infections (e.g. Chlamydia) Genetic analyses

Analyses in men	Unfulfilled desire to have a child	Center for cryopreservation
Semen analysis Sperm preparation for intrauterine insemination (IUI) DNA fragmentation in sperm (HALO) Diagnostic preparation of sperm Post-vasectomy checkup	Treatment in collaboration with gynecologists, FMH specialists in reproductive medicine In vitro fertilization (IVF) Intracytoplasmic sperm injection (ICSI) Intracytoplasmic morphologically selected injection of sperm (IMSI) IVF / ICSI / IMSI in natural cyclus Blastocyst culture Assisted Hatching	Freezing and storage of sperm from ejaculate or testicular biopsy Freezing and storage of oocytes Freezing and storage of zygotes

Kinderwunschzentrum Regio Basel

Schifflände 3
4051 Basel

T +41 61 261 44 03
F +41 61 261 44 02

CARE – Centrum für Assistierte Reproduktionsmedizin
und Gynäkologische Endokrinologie, Biel

Rüschlistrasse 9
2502 Biel

T +41 32 499 09 09
F +41 32 499 09 10